utilities

Dr Laura Phipps

Does Down’s syndrome hold the key to cracking Alzheimer’s?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsFaye Monk

It can come as a surprise to know that having Down’s syndrome puts people at much higher risk of Alzheimer’s. In fact, the genetic rearrangement that causes Down’s syndrome is one of the greatest genetic risk factors for Alzheimer’s. Sadly, everyone with Down’s syndrome will have developed the characteristic plaques and tangles of Alzheimer’s in […]

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How many people develop Alzheimer’s in their 30s?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsFaye Monk

This week we’re helping Rita Pepper speak out about how Alzheimer’s has affected her family. Her daughter Carla, who now lives in a care home, was diagnosed with a genetic form of the disease when she was in her 30s. Rita’s husband Barry also developed Alzheimer’s and passed away at the age of 43. This […]

People power unlocks the secrets of human spatial navigation

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsFaye Monk

In May, we worked with Deutsche Telekom and researchers at University College London (UCL) and the University of East Anglia (UEA) to launch Sea Hero Quest. This fun game got you sailing through sunkissed tropical seas and memorising maps of stormy shores – all in the name of research. The value of Sea Hero Quest […]

Silver lining for first anti-tau Alzheimer’s treatment in phase III?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsFaye Monk

Findings were reported today from the first phase III anti-tau drug in people with mild-to-moderate Alzheimer’s. The drug, called LMTM, was being tested in a 15-month double-blind, controlled trial in 891 people. Sadly, the drug failed to meet the aims it set out to, but there may be a silver lining for the small number who […]

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Who is most at risk of dementia?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsFaye Monk

Dementia is the most feared diagnosis in the over 55s in the UK, affecting around 850,000 people across the country. You often ask us why some people develop the condition and others don’t, and whether it’s possible to predict who will go on to get dementia. Predicting who will develop dementia is not an easy […]

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The immune system – a wolf in sheep’s clothing in Alzheimer’s?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsFaye Monk

Our immune systems are vital for keeping us healthy. This complex defence mechanism is made up of an army of millions of cells circulating in the blood and patrolling in our tissues. This army is made up of ‘battalions’ of cells with slightly different roles in identifying, alerting, destroying and clearing up damage in our […]

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An update on our research

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsFaye Monk

It’s a fast-moving and ambitious time for dementia research, with lots of new projects getting underway. Here is just a snapshot of what’s been happening during May. UCL Drug Discovery Institute formally opens Our Drug Discovery Alliance is an ambitious network of Institutes with dedicated in-house drug discovery experts who are working with academic researchers […]