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Learning from cancer research in the hunt for dementia treatments

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

On the final day of last month’s Alzheimer’s Association International Conference in Toronto, we heard from Dr Jane Ann Driver, a cancer scientist who moved disciplines and took the leap into dementia research. This experience gave her a valuable perspective on dementia research, allowing her to impart lessons learned in cancer research and to highlight important […]

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Researching risk reduction

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

On the blog earlier this week we talked about the latest research to identify the people who are most at risk of dementia. Our age and our genes are two of the biggest risk factors for dementia and, no matter how hard we try, there’s nothing we can do to change who our parents are […]

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Behind the headlines: what’s the real story for LMTX?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

The UK public woke up this morning to a series of headlines about phase III trial results of a potential Alzheimer’s drug called LMTX (also known as LMTM). The Times (£) placed their report on the front page, while the story was also reported by the Daily Mail, the Daily Express, BBC Online and more. […]

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Silver lining for first anti-tau Alzheimer’s treatment in phase III?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

Findings were reported today from the first phase III anti-tau drug in people with mild-to-moderate Alzheimer’s. The drug, called LMTM, was being tested in a 15-month double-blind, controlled trial in 891 people. Sadly, the drug failed to meet the aims it set out to, but there may be a silver lining for the small number who […]

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Who is most at risk of dementia?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

Dementia is the most feared diagnosis in the over 55s in the UK, affecting around 850,000 people across the country. You often ask us why some people develop the condition and others don’t, and whether it’s possible to predict who will go on to get dementia. Predicting who will develop dementia is not an easy […]

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The immune system – a wolf in sheep’s clothing in Alzheimer’s?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

Our immune systems are vital for keeping us healthy. This complex defence mechanism is made up of an army of millions of cells circulating in the blood and patrolling in our tissues. This army is made up of ‘battalions’ of cells with slightly different roles in identifying, alerting, destroying and clearing up damage in our […]

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Is Alzheimer’s written in your genes?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

Research updates from Alzheimer’s Association International Conference 2016 This week dementia researchers from six continents, hundreds of research institutions and countless different backgrounds have made their way to Toronto for the world’s largest meeting of dementia researchers – the Alzheimer’s Association International Conference 2016. Clinicians and pharmacologists will rub shoulders with cell biologists and geneticists […]

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