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Why is dementia research the elephant in the room?

Dr Matthew Norton

This is a cross Blog post with Age UK With the Care Bill running through parliament, the development of historic reform of the funding system for social care and much political focus on the integration with the health system. One could be forgiven for thinking that the Gordian Knot that is health and social care […]

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Neurodegeneration – a common cure?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

Today’s papers are reporting a ‘potential breakthrough’ in treating all neurodegenerative disorders. Surely this sounds too good to be true? Let’s look in a bit more detail at the concept behind this research… What do neurodegenerative diseases have in common? The term ‘neurodegenerative disease’ covers a whole span of conditions, all resulting in the loss of nerve […]

Down’s syndrome and dementia: what’s the link?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

It often comes as a surprise to people that there’s a link between Down’s syndrome and dementia. But more than 60% of people with Down’s syndrome will develop Alzheimer’s – the most common form of dementia – before the age of 60. With our help, scientists are unravelling why. Genetic duplication in Down’s syndrome The […]

When is a failed clinical trial not a failure?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

Back in 2002, the news broke that Elan had halted its phase II clinical trial for the AN1792 vaccine, designed to combat Alzheimer’s. It was a severe disappointment for people with Alzheimer’s and their loved ones. Many hopes had been pinned on the vaccine, and its failure saw those hopes dashed for hundreds of thousands […]

World Alzheimer’s Day: How you can make a difference in research

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

Today is World Alzheimer’s Day. No doubt the day will mean something different to everyone touched by Alzheimer’s or another form of dementia. For some, it’s an opportunity to think about those we know affected by dementia, or those who are no longer here. For others, a chance to raise awareness or think about how […]

When Alzheimer’s steals your sight

Tim Shakespeare

What is posterior cortical atrophy? Posterior cortical atrophy (PCA) is a rare condition most often caused by Alzheimer’s disease but surprisingly, despite often having the same underlying disease, people with PCA have a striking difficulty in seeing what and where things are, while their memory for recent events can still be very good. The visual […]

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Alzheimer’s disease and the cocktail party effect

Hannah Golden

Alzheimer’s disease is mostly thought of as a memory problem. But as many who deal with the disease know, this isn’t the only problem people experience. Many patients come into clinic reporting difficulty following conversations in busy rooms, or hearing someone over a busy phone line. We’re trying to find out why people with Alzheimer’s have these problems, and what this can tell us about Alzheimer’s disease as a whole.

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