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Tag Archives | Failed drug trials

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Dementia Forum 2015 report: a global call to action

Dr Matthew Norton

Today’s headlines feature a new report from the World Innovation Health Summit Dementia Forum 2015, which underlines the need for global action to tackle dementia. The report makes recommendations to help fight dementia – including steps to attract new investment for research – and outlines some of the obstacles that have hampered research so far. […]

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The Global Clinical Trials Fund: drugs and dummies

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

Today marks one year since the G8 Dementia Summit. The last year has been a whirlwind of new investment and exciting initiatives, both from Alzheimer’s Research UK and government, all with one aim: to bring us closer to a treatment for dementia. But we mustn’t lose momentum. Today, we are pleased to announce our newest […]

The failure rate of clinical trials for Alzheimer’s – why we need to raise our game

Dr Simon Ridley

This is a cross blog post with Alzheimer’s Research & Therapy. Dementia is the name for a collection of many different conditions, of which Alzheimer’s disease is the most common. Alzheimer’s is characterised by a gradual decline in memory and changes in behaviour and communication. In the later stages, people often forget their friends and family […]

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When will there be new Alzheimer’s treatments?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

We desperately need new treatments for Alzheimer’s. While current treatments can help people with symptoms, over 100 years of research hasn’t given us a treatment that can stop this devastating disease. But we are getting closer, with more treatments than ever before in development. Targeting the disease process Understanding the processes in the brain that […]

What to expect from the next five years of dementia research

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

Yesterday, our Director of Research Dr Eric Karran spoke about his hopes for the development of new Alzheimer’s treatments, saying that he is ‘more encouraged for the future now, than he has ever been’. This rallying call comes only a few days before the G8 dementia summit takes place in London. The G8 event will […]

When is a failed clinical trial not a failure?

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

Back in 2002, the news broke that Elan had halted its phase II clinical trial for the AN1792 vaccine, designed to combat Alzheimer’s. It was a severe disappointment for people with Alzheimer’s and their loved ones. Many hopes had been pinned on the vaccine, and its failure saw those hopes dashed for hundreds of thousands […]

Right drug, right patient, right time

Dr Laura PhippsKirsty MaraisClaire LucasRobin BrisbourneKaty StubbsEd PinchesGlyn Morris

This month we’ll be at the political party conferences urging all parties to continue to back dementia research. With no new drugs since 2003, and those in existence only showing modest efficacy, we desperately need new treatments that can delay the onset, slow the progression and manage the symptoms of dementia. Only through research can we make progress and offer hope to people with dementia.